Hey Sister! & Khapregesic®
Khapregesic® is the main ingredient in all of our Hey Sister! products. Khapregesic® is a plant-based active ingredient. Developed with advanced technology, Khapregesic® retains the natural profile of compounds found in the Khaya senegalensis tree (pronounced Ky-yar sen-ee-gal-en-sis), also known as Khaya (Ky-yar for short).
Khapregesic® (Khaya senegalensis dry stem bark) is traditionally used in Western herbal medicine to relieve menstruation pain, symptoms of premenstrual tension, and symptoms of menopause, including hot flushes, night sweats, and mood swings.
OG Range (our original formula): is packed with our single hero ingredient Khapregesic® - specifically focusing on the therapeutic relief for those managing period pain & PMS. OG is also HASTA certified, meaning this range is safe for athletes to use. HASTA is the only laboratory in Australia able to provide independent Certification of sport supplements by testing for WADA prohibited substances.
Life Range: as with OG, Life is packed with our hero ingredient Khapregesic®, however each stage of our Life Range, from Teen Period through to Menopause, includes added vitamins that are critical to the wellbeing of a woman at each stage of Life. The added vitamins have been carefully selected, by women, for women.
Think of the Life range as a multivitamin designed for your specific stage of Life, with the added benefits of Khapregesic® - packing an even more powerful punch.
Our Khaya Trees are grown in Western Australia on our own Australian USDA Certified Organic plantations, where it’s sustainably cultivated using patent-pending harvest technology, ensuring that our trees thrive post-harvest, creating a renewable natural resource while storing carbon to benefit the planet.
The hero ingredient in Hey Sister!, Khapregesic®, is 100% Australian grown and made with no offshore processing. It’s local, clean, and traceable from soil to shelf.
You can read more about this on our science page!
https://heysister.com/pages/our-science
Effectiveness & expectations
As with medicines containing natural active ingredients, results can be different for everyone; our bodies are unique. Even more importantly, everyone's pain journey is different. While some may notice a difference quickly, others find it takes regular use over 2 to 3 cycles. Many people make the mistake of not completing the full recommended dosage and duration during their cycle, which means you may not notice the full impact. For more information see the 'How do I take Hey Sister!' FAQ.
Directions & practical tips
Please always read the label and follow the directions for use.
Dosage
- OG Range (Original): Take 1 tablet morning and night (2 tablets per day).
- Life Range: Take 2 tablets morning and night (4 tablets per day).
Take with or without food, or as professionally prescribed.
Timing
For best results with period pain and PMS, we recommend starting 2–3 days before your period is due. This helps relieve symptoms of premenstrual tension, including mild anxiety and mood swings, before they peak.
Duration & Safety
Continue taking the tablets as recommended during your period or symptom flare-up.
Important: Do not use for more than 7 days at a time. This product is not for prolonged use and may harm the liver.
Yes, you can crush Hey Sister! tablets if swallowing them whole is difficult. They can be mixed with a little water, juice, or a spoonful of yoghurt. The tablets will still do their thing, just note the taste can be a bit earthy, so we suggest a little honey to help the mixture from being too bitter.
If your period is irregular, we recommend taking Hey Sister! at the first sign of PMS symptoms, or period pain. Hey Sister! has been designed to work quickly, this means that you can take is as soon as you start to feel the need.
Buying, shipping & subscriptions
You can purchase Hey Sister! directly on our website, it’s free shipping and we offer a money back guarantee if Hey Sister! Does not work for you.
Hey Sister! is also available in 700+ pharmacies. Find your nearest pharmacy using our store locator:
https://heysister.com/pages/find-a-store
We also offer a subscription model, which means each month, or quarter, we will automatically ship out your chosen Hey Sister! Product, ensuring you don’t ever run out, this is also a cheaper option for you.
Hey Sister! ships Australia-wide (and to selected international locations). Orders are usually processed within 1–2 business days, with tracking available once dispatched.
We ship our products worldwide from Australia using international express shipping. No matter where you are, we'll make sure your order reaches you as quickly as possible.
You can skip, reschedule, advance or cancel your subscription at any time using our subscription management portal.
Just login here using your email address (we will send you a one-time verification code).
Yes! All Hey Sister! products come with a money-back satisfaction guarantee on any 1 transaction within the last year. Please note that individual results may vary, and this guarantee does not imply the product is effective in all cases.
Read the full terms and conditions here.


