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Caroline Robertson

Naturopath, Anatomy and Physiology lecturer, and writer with over 35 years’ experience specialising in women’s health.

Dealing with debilitating period symptoms each cycle?

Is The Hype For This New “Upgraded Painkiller” Justified?

If You Struggle With Unbearable Period Pain - Here's Why...

Caroline Robertson, naturopath with over 35 years of experience, shares the misunderstood reasons behind crippling period symptoms that leave so many women feeling helpless. Most importantly, she’ll share a safe, natural solution to help you break free from the monthly agony and reclaim control of your life.

  • Learn why your period symptoms are so unbearable.
  • Why traditional pain relief doesn’t work for you.
  • And how to target the cause for lasting, natural relief.

Taking the Pain Out of Period Pain

“Why am I cursed with these cramps every month?”

One of my patients exclaimed in a defeated tone. Sadly, she’s not alone. If you’ve ever found yourself curled up in agony, unable to stand upright, and dreading that time of the month, you know exactly how she feels.As a Naturopath specialising in women’s health for 35 years, I’ve seen how dysmenorrhoea (severe period pain) can take over a woman’s life. Because it’s not just a couple of bad days - it’s intense physical pain, emotional strain, and a constant reminder that your body feels out of control - all of which can last for weeks!My patient Chloe for example, relied on painkillers to get through her day, but the more she depended on them, the more worried she became:

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“I don’t want to create more problems from taking pills… I’d rather get natural relief.”

You and Chloe are not alone,  many women feel trapped - caught in a cycle of pain, fear, and frustration as nothing seems to help those intense period symptoms.

Some endure nausea, faintness, or repeated hospitalisations before getting a diagnosis to their problems. For my client Rose, it was endometriosis - a condition affecting 190 million women worldwide. For some sufferers, it's adenomyosis, fibroids, or PCOS. But for most, they don’t know what’s the true cause behind their misery. All they know is that no matter what they try, it never seems to work!

So what could it be?

The Common Thread: Inflammation

Across all these conditions and the intense symptoms that follow, one factor stands out: inflammation. When your body’s inflammatory response skyrockets around your cycle, it triggers unbearable cramps and other debilitating symptoms.

The good news? Reducing inflammation often reduces pain. Accepting that inflammation plays a critical role is empowering - it means your body isn’t broken. There’s a treatable cause behind the suffering.

Why Inflammation Happens

During your cycle, your body produces prostaglandins to help shed the uterine lining. But when inflammation is heightened, these substances can spiral out of control, causing severe cramps. Stress, poor gut health, processed foods, and conditions like endometriosis only fuel this loop: more inflammation, more pain, more stress.

Having worked with hundreds of women, one thing is clear: calming the inflammation in your body can bring genuine, lasting relief.

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You Don't Need Another Quick Fix

  • Not Comprehensive: They mute pain but don’t address other - just as debilitating - symptoms like bloating, mood swings, or fatigue.
  • Side Effects: Use of painkillers like ibuprofen come with a bunch of side effects, ranging from nausea to kidney and liver damage.
  • Long-Term Risks: Regular and long term use raises the risk of ulcers and cardiovascular issues among other risks.
  • Surface-Level Relief: Some painkillers like paracetamol doesn't even target inflammation, leaving the root cause untouched.
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You can take alternative approaches to decreasing inflammation. Dietary changes, like avoiding processed foods and sugar, can help reduce inflammation, but they’re rarely enough for severe, hormone-driven symptoms. When you’re doubled over in pain, food tweaks alone won’t deliver the powerful relief you need.

The Ideal Middle Ground: Safe and Powerful Anti-Inflammation

What’s needed is a solution strong enough to tackle the worst cramps, yet gentle enough to use regularly. Natural, herb-based anti-inflammatories strike this balance perfectly, offering powerful relief without the risks of pharmaceuticals.

How To Pick the Right Solution

Regardless of what solution you choose to tackle your period symptoms, here's the things to look for which will deliver the best results:

  • Safe for Long-Term Use: Find something that can provide relief month after month, with no harmful side effects.
  • Proven to Work: Choose remedies backed by historical use and modern clinical trials.
  • Trusted by Experts: Advice from experienced healthcare providers matters. Generally, if it's recommended by a healthcare provider or expert -  it's more trustworthy. 
  • Easy to Use: Look for something simple to incorporate into your routine.
  • Targets Inflammation: Don’t settle for surface fixes - find something that treats the root cause - inflammation.
  • Comprehensive: It should alleviate all your symptoms, not just cramps or pain.
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Painkillers are NOT the Solution

For strong period pains, cramps and other symptoms. Painkillers aren't always the best solution because of the side effects. Instead, you need something safer for regular use and ideally more comprehensive at addressing multiple symptoms.

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Why I Recommend Hey Sister! Period

If you’re looking for a natural solution to tackle inflammation, look no further than Hey Sister Period. This specialised formula combines Khapregesic® - a highly bioavailable form of Khaya senegalensis - with supportive nutrients for a truly comprehensive approach to menstrual care.

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Why Women Choose Hey Sister Period Over Other Herbal Remedies

  • Safe for Long-Term Use: It can be used each cycle without the worry of side effects or unintended effects.
  • Genuine Relief: Not only is it natural, but it can also provide genuine relief that'll rival your pharmaceutical based painkillers.  
  • Comprehensive: From cramps to mood swings, Hey Sister! is able to address many of the symptoms that make your periods so debilitating.

How It Works

Khapregesic® moderates prostaglandin production, easing painful cramps at their source. Coupled with antioxidants and prebiotics, it delivers holistic relief - physically, mentally, and digestively.

  • Reduces Inflammation: Attacks the root cause of severe pain and cramps.
  • Boosts Energy and Mood: High antioxidant levels combat fatigue and PMS symptoms.
  • Eases Bloating: Natural prebiotics support gut health for better digestion and bloating relief.
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Real Stories, Real Relief

The results from using Hey Sister! aren't just experienced by a few lucky people. Over 4,000 women use Hey Sister! as part of their period routine to get genuine, natural period pain relief. Here's what a handful of them had to say about their experience...

“My number one go to these days is Khapregesic®, a powerful anti-inflammatory, anti-spasmodic, antioxidant, digestive and relaxant.”

Naturopath Angela Harrison (@angelaharrisonhealth).
Recommends Khapregesic® to her patients, especially those with severe period pain.

“It’s an absolute game changer in the pain department. As someone who suffers from month long endometriosis and chronic period pain, my first period with this felt so minimal and my endo flares throughout the month aren’t as painful either.”

Vanessa A.
Shares her dramatic improvement after using Hey Sister! Period Pain.

“I just tried this for the first time and it worked! Each month I use pain killers for my cramps but this stops them!”

Jennifer
First tried Hey Sister Period in November 2024 and was thrilled with the results.

“My 16-year-old daughter was experiencing nausea, vomiting, back pain, headaches and cramping every cycle. Only one cycle of Hey Sister! and there was none of these! No days in bed, no medication, no heat packs!! It seems unbelievable but it’s true. Such a relief for both of us that we have found something.”

Renee C.
Is over the moon about her daughter’s positive response.

As a mother, I’ve seen Hey Sister Period transform my own daughter’s life. The next time her cycle approached, instead of dreading it, she simply asked, “Hey Mumma, can I have some Hey Sister, please?”

You don’t have to endure crippling cramps. Confront inflammation - the real root of your period torment - with a safe, herbal solution that works.

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Hey Sister! Period

Packed with potent anti-inflammatory properties, Hey Sister! Period is proven effective at reducing strong period pains, cramps, bloating, mood swings and more.

Buy Now

Clinical Research

Supported by Data

A recent randomised, double-blind, placebo controlled clinical trial conducted by Clinical Research Australia on Khapregesic® vs a placebo(1) found the following:

230%

Khapregesic® had over 230% more pain relief/reduction than the placebo group

170%

Over 170% improvement in physical wellbeing than the placebo group

300%

Close to 300% improvement in emotional wellbeing than the placebo group

400%

a 400% improvement in Social Functioning than the placebo group

(reduced time off from work, school, social functions and life in general)

100%

100% safe - Khapregesic® had no significant effect on all blood markers which were all within normal limits

98%

98% of participants reporting good to excellent tolerability taking 6 tablets per day for 28-35 days.

(1) The Khapregesic® Clinical Trial was completed in January 2025 and is awaiting publication.

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NARP - Not a Real Product
NARP - Not a Real Product
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NARP - Not a Real Product
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Noah B.

"Helps stabilise my mood nearly as much as anti-anxiety meds and reduces my cramping so much that I don't need any other painkillers despite my endo"

  • Verified Buyer

Rachel A.

"I was skeptical but hopeful and surprisingly after just a day I felt this working! My pain is random and can happen anytime but lately almost daily, so this is a great solution for me."

  • Verified Buyer

Hey Sister! Period.

Backed by science and proven to help relieve intense period symptoms and promote overall wellness for women.

NARP - Not a Real Product
NARP - Not a Real Product
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NARP - Not a Real Product
NARP - Not a Real Product
NARP - Not a Real Product
NARP - Not a Real Product
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We recommend new customers allow up to 3 menstrual cycles to see full benefits. Start with a discounted 3 month supply.

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If You Don't Fall Head Over Heels In Love With Our Products, We'll Give Your Money Back. No time restrictions. Just Ask.

The Science Behind Hey Sister!

Hey Sister! Period is a new, natural remedy proven to reduce multiple menstruation symptoms at once. It harnesses the power of strong, plant-based anti-inflammatories in its hero ingredient, Khapregesic®, to bring effective relief that targets the root cause.

What Causes Period Symptoms

For most women, menstruation can bring symptoms like cramps, bloating, mood swings, heavy bleeding and fatigue. The cause of these symptoms typically stems from an overproduction of prostaglandins - a hormone-like substance that influences inflammation, pain, and uterine contractions. The excess of prostaglandins during menstruation increases inflammation, sparking these common period symptoms and often making them more intense than normal.

How Khapregesic® Works

Khapregesic® is powered by a single, natural ingredient known for its strong anti-inflammatory effects[1], high antioxidants[1], and naturally occurring prebiotics[2]. This unique combination helps to ease period symptoms by reducing prostaglandin levels, which, in turn, decreases inflammation and alleviates discomfort. The result? Symptom-free relief that's natural.

Why Choose Hey Sister!

We know that every woman’s period is different, and there’s no one-size-fits-all approach to menstrual relief.

But we also understand that there's a need for a natural, effective alternative to traditional painkillers - one that offers relief without the need for synthetic drugs.

That’s exactly why we created Hey Sister! Period. Our plant-based solution provides powerful, natural symptom relief while supporting long-term wellness without the harmful side effects often associated with drug-based painkillers.

Unlike standard pain medications, Hey Sister! goes beyond simple symptom relief. Each tablet is packed with antioxidants and prebiotics to boost gut health, immunity, and energy levels.

For holistic, comprehensive support through your cycle, Hey Sister! is here to help you feel balanced, healthy, and at ease, every month.

What's Inside It?

Each tablet contains:

Khapregesic® 500 mg (Khaya Senegalensis Dry Stem Bark).

Our products are manufactured in Australia from Australian-grown certified-organic Khaya Senegalensis.

100% Plant-based. No added artificial flavouring, colouring or preservatives.

Free from dairy, gluten, eggs, nuts, and yeast.

Hey Sister! is regulatory approved. Registration numbers AUST L 315762, 407536, 407537.

How Should I Take It?

Take 2 tablets daily, one in the morning and one in the evening, with or without food and continue for 7 days or as professionally prescribed.

If symptoms persist, talk to your health professional.

Children: Use in children under 12 years is not recommended.

Pregnancy: Do not take if you are likely to become pregnant, pregnant, or breastfeeding.

For a full set of directions always refer to the pack.

Click to Read More FAQs

Noah B.

"Helps stabilise my mood nearly as much as anti-anxiety meds and reduces my cramping so much that I don't need any other painkillers despite my endo"

  • Verified Buyer

Rachel A.

"I was skeptical but hopeful and surprisingly after just a day I felt this working! My pain is random and can happen anytime but lately almost daily, so this is a great solution for me."

  • Verified Buyer

Expert Reviews

Trusted by Health Practitioners

Jade Walker

Director of Health & Wellness, Hey Sister! and Naturopath (Bachelor of Health Science)

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I’ve been using Hey Sister! for almost five years now. I used to experience intense period pain and had tried just about every natural remedy under the sun. But this is the only product that actually comes close to delivering fast and effective relief like conventional options do.

And it’s not just about pain relief. This is a next-generation solution that’s rich in plant polyphenols, supporting tissue repair, gut health, and overall wellbeing. It’s about bloody time we had a better option — and Hey Sister! is it.

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Caroline Robertson

Naturopath, Anatomy and Physiology lecturer, and writer with over 35 years’ experience specializing in women’s health.

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Reflecting on my own history with painful periods, I wish I’d had Hey Sister! Period sooner. But I’m profoundly grateful to share it now - especially with women who feel like they’ve tried everything else to no avail. You don’t have to silently endure crippling cramps. Confront the real root of your period torment - inflammation - with a safe, herbal solution that genuinely works.

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Frequently Asked Questions

Is It Actually Effective?

Yes, Hey Sister! is a genuinely effective solution to reduce your period pains, cramps and other mensuration symptoms. Besides the fact it’s been used for centuries in Western herbal medicine to reduce inflammation and pain, research and clinical studies can back up the claims we make about the effects of our products.

We're one of the few companies in the women's health space that takes efficacy seriously and have spent our own money to put our products to the test in clinical settings. We have a few recent observational trials underway and are committed to releasing the findings once they've concluded - as we've done with previous trials. 

What Symptoms Can It Relieve?

Hey Sister! Period offers comprehensive menstruation symptom relief and is proven to help reduce or relieve the following symptoms:

  • Menstruation Pain / Dysmenorrhoea.
  • Menstrual Spasms / Cramps.
  • Heavy Menstruation / Periods.
  • Weariness / Tiredness / Fatigue / Feeling of Weakness.
  • Abdominal Bloating / Spasm.
  • Gastrointestinal Pain.
  • Occurrence of Premenstrual Tension Symptoms (PMS).
  • Feelings of Aggression / Irritability Associated with Premenstrual Tension.
  • Mood Changes / Mood Swings Associated with Premenstrual Tension.
  • Breast Pain / Tenderness Associated with Premenstrual Tension.
  • Confusion Associated with Premenstrual Tension.
  • Symptoms of Mild Anxiety.
  • Symptoms of Heartburn.
Is It Safe? Are There Any Side Effects?

Yes, Hey Sister! is considered safe for use every period cycle. Out of all the research done on our active ingredients, there's not been one report of harmful side effects. Additionally, a part of what makes Hey Sister so safe to use especially, on a regular basis is the fact that our active ingredients are water soluble and will flush out the body just like a vitamin would once you stop taking it - there's no build-up, lingering effects, or tolerance build-up.

How Long Until I See Results?

With Hey Sister! Period, most customers report immediate results - at worst - you'll feel the difference same day you start taking it regardless of when you start taking it during your period.

For best results, we recommend you start dosage 1-2 days before your period, or at least as soon as you experience symptoms.

For full, comprehensive results, we recommend taking Hey Sister! for at least 3-period cycles.

If you're skeptical about our products working for you, we provide all new customers with a "Love It Or Money Back" guarantee on all first orders - so there's nothing to lose and everything to gain from trying us out!

How Should I Take It?

Take 2 tablets daily, one in the morning and one in the evening, with or without food and continue for 7 days or as professionally prescribed.

If symptoms persist, talk to your health professional.

Children: Use in children under 12 years is not recommended.

Pregnancy: Do not take if you are likely to become pregnant, pregnant, or breastfeeding.

For a full set of directions always refer to the pack.

What's Inside Hey Sister! Period?

Each tablet contains:

Khapregesic® 500 mg (Khaya Senegalensis Dry Stem Bark).

Our products are manufactured in Australia from Australian-grown certified-organic Khaya Senegalensis.

100% Plant-based. No added artificial flavouring, colouring or preservatives.

Free from dairy, gluten, eggs, nuts, and yeast.

Hey Sister! is regulatory approved. Registration numbers AUST L 315762, 407536, 407537.

Can I Take It With Other Medications?

Yes, Hey Sister! can be taken safely at any time and with any other food, supplement or medication.

What If It Doesn't Work For Me?

Periods are complex, and our bodies even more so. We would be  surprised if you didn't feel any benefit from taking Hey Sister! especially when taken as directed. But if you're one of the unlucky few who don't, don't stress, we got your back.

We provide all new customers with a "Love It Or Money Back" guarantee on all first orders - so there's nothing to lose and everything to gain from trying us out!

Don't be afraid to contact support if you find it doesn't work as expected or if you need help with proper use or dosing.

How Long Does Shipping Take?

Orders are processed and dispatched within 24 hours of being received (during weekdays) and should arrive approximately 2 – 10 working days from dispatch depending on the address location.

Although once we ship it out, delivery times are out of our control and subject to Australia Post shipping times, we'll do our best to ensure a speedy arrival and assist with any shipping related support questions or concerns you have.

If you need a speedy delivery we offer a discounted express shipping option, just select it at checkout.

How Do I Manage My Subscription?

You can manage your subscriptions and view order history by logging in and navigating to heysister.com/account.

Alternatively, contact our support at support@heysister.com, or leave us a message on our live chat.

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*Regulatory claims

Traditionally used in western herbal medicine to: [PERIOD] relieve menstruation pain, reduce occurrence of abdominal bloating, relieve symptoms of mild anxiety, reduce mood swings associated with premenstrual tension, [MENOPAUSE] reduce occurrence of menopausal symptoms, relieve symptoms of mild anxiety, reduce heavy menstruation (during peri-menopause).

Always read the back of the pack and if symptoms persist, seek the advice of a healthcare professional.

Regulatory Reg. Nos. AUST L 315762, 407536, 407537. AU and US Certified-Organic No: 11640

© Hey Sister! 2024 BioActive Natural Health Pty Ltd

Sources

[5] Barg, C., & Robertson, C. (2019). Khaya senegalensis: Discover Khaya, the period pain reliever. Journal of the Australian Traditional Medicine Society, 25(3), 148. ISSN 1326-3390.

[4] Direct, H. (2024) Liver failure, healthdirect.gov.au. Available at: https://www.healthdirect.gov.au/liver-failure#:~:text=low%20blood%20pressure-,Paracetamol%20overdose%20is%20the%20most%20common%20cause%20of%20acute%20liver,Centre%20on%2013%2011%2026. (Accessed: 2024).

[3] Gow PJ, Jones RM, Dobson JL, Angus PW. Etiology and outcome of fulminant hepatic failure managed at an Australian liver transplant unit. J Gastroenterol Hepatol 2004; 19: 154-159.

[2] CHARACTERIZATION OF BIOACTIVE PHYTOCHEMICALS FROM THE STEM BARK OF AFRICAN MAHOGANY Khaya senegalensis (MELIACEAE) Huaping Zhang 12-2008; https://tigerprints.clemson.edu/all_dissertations/305/. Journal of the Australian Traditional Medicine Society Vol25 No3 2019 pp146-149. Journal of the Australian Natural Therapists Association Vol34 No3 2020 pp63-65

[1] Anticancer Research (2006) 26(3 B) 2397-2405 Chemopreventive effects of Khaya senegalensis bark extract on human colorectal cancer; Androulakis X, Muga S, Chen F, et al; https://www.mendeley.com/catalogue/f7090483-0e6d-300e-8a4e-8ba7ac808564/. Journal of the Australian Traditional Medicine Society Vol25 No3 2019 pp146-149. Journal of the Australian Natural Therapists Association Vol34 No3 2020 pp63-65